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DeCS
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Descriptor English:
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Protamines
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Descriptor Spanish:
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Protaminas
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Descriptor Portuguese:
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Protaminas
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Synonyms English:
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Chloride, Protamine
Protamine Chloride
Protamine Sulfate
Sulfate, Protamine
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Tree Number:
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D12.776.660.750
D12.776.664.750
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Definition English:
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A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692) |
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Indexing Annotation English:
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heparin antag
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Pharmacological Action:
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Heparin Antagonists
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Allowable Qualifiers English:
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Record Number:
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23432
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Unique Identifier:
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D011479
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Occurrence in VHL:
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Similar:
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DeCS
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